Indirect treatment comparisons (ITC) and mixed treatment comparisons (MTC) are increasingly used in health technology assessment. They are statistical techniques to synthesise available direct and indirect evidence to provide information on the comparative effectiveness of a range of competing interventions.
Indirect treatment comparisons and mixed treatment comparisons are often the end product of systematic reviews and the data produced is often used to inform economic models. Deciding on the suitability of conducting these analyses and undertaking them require a range of specialist skills including statistical skills. These analyses also significantly benefit from appropriate scoping and advanced planning.
YHEC offers this one day training workshop to introduce indirect treatment comparisons and mixed treatment comparisons to project managers, research commissioners and others new to these techniques, to help them understand how to plan, commission and assess indirect treatment comparisons/mixed treatment comparisons. The workshop is currently presented on-demand at the client’s choice of location. Click below to find out about customisable training options:
The trainers are experienced statisticians, modellers and researchers, who have conducted a range of indirect and mixed treatment comparisons to inform reimbursement decisions and global economic models. Find out more about YHEC and Quantics’ Indirect Treatment Comparison work here
- Dr Matthew Taylor, Director, York Health Economics Consortium, University of York
- Kelly Fleetwood, Principal Statistician, Quantics
- Julie Glanville, Associate Director, York Health Economics Consortium, University of York
The training team can be two or three people depending on requirements.
By the end of the training day, participants will:
- Understand the principles of indirect treatment comparisons and mixed treatment comparisons;
- Understand the preplanning and scoping required to inform the indirect treatment comparisons/mixed treatment comparisons;
- Understand the limitations of indirect treatment comparisons /MTC and when such analyses may not be appropriate;
- Be aware of the key issues to specify in a request for proposal and to explore when assessing the suitability of a completed proposal;
- Understand the resource implications of such comparisons.
This training day will be of value to:
- Project managers, research commissioners and researchers commissioning indirect treatment comparisons/mixed treatment comparisons which inform larger projects such as models and who need to understand how to specify the ITC/MTC in a request for proposal or invitation to tender.
- Researchers new to the field of indirect treatment comparison/mixed treatment comparisons wishing to gain an overview of the techniques, strengths and limitations of the techniques and the resources required.
It should be noted that this course is not a hands-on guide toward undertaking indirect treatment comparisons or mixed treatment comparisons, but is aimed towards those who need to interpret and understand them.