YHEC offers a range of reviewing services from scoping reviews and rapid evidence reviews, through to systematic reviews and indirect/mixed treatment comparisons.
YHEC undertake systematic reviews for a variety of purposes:
- To review effects, adverse effects, cost-effectiveness and health-related quality of life (HRQOL) evidence to inform Single Technology Appraisals (STA) for NICE and submissions to other agencies;
- To identify gaps in research;
- To inform the development of economic models;
- To summarise health-related quality of life.
Indirect or mixed treatment comparisons
In collaboration with our partners at Quantics Consulting, we also undertake indirect or mixed treatment comparisons, allowing effectiveness data to be generated for different treatment where head-to-head data are not necessarily available. Read more about our indirect or mixed treatment comparison services.
To find out more about YHEC’s systematic reviewing services contact Julie Glanville.
Systematic Reviewing Clients
YHEC has recently worked with European Food Safety Authority (EFSA), NHS Improving Quality, the National Institute for Health and Care Excellence (NICE), Danone Institute International and pharmaceutical, food and device companies to provide systematic reviews, research evidence and evidence tools.
Examples of Recent Publications
- Danyliv A, Glanville J, McCool R, Ferreira A, Skelly A, Jacob RP. The Clinical Effectiveness of Ranibizumab Treat and Extend Regimen in nAMD: Systematic Review and Network Meta-Analysis. Adv Ther 2017
- McCool R, Gould IM, Eales J, Barata T, Arber M, Fleetwood K, Glanville J, Kauf TL. Systematic review and network meta-analysis of tedizolid for the treatment of acute bacterial skin and skin structure infections caused by MRSA. BMC Infect Dis. 2017 Jan 7;17(1):39.
- Perry AE, Woodhouse R, Neilson M, Martyn St James M, Glanville J, Hewitt C, Trépel D. Are Non-Pharmacological Interventions Effective in Reducing Drug Use and Criminality? A Systematic and Meta-Analytical Review with an Economic Appraisal of These Interventions. Int J Environ Res Public Health. 2016 Sep 29;13(10). pii: E966.
- O’Connor S, Hanlon P, O’Donnell CA, Garcia S, Glanville J, Mair FS. Barriers and facilitators to patient and public engagement and recruitment to digital health interventions: protocol of a systematic review of qualitative studies. BMJ Open. 2016 Sept 2; 6 (9).
- Glanville J, Ludwig T, Lifschitz C, Mahon J, Miqdady M, Saps M, Hock Quak S, Lenoir-Wijnkoop I, Edwards M, Wood H, Szajewska H. Costs associated with functional gastrointestinal disorders and related signs and symptoms in infants: a systematic review protocol. BMJ Open. 2016 Aug 24;6(8):e011475.
YHEC Systematic Review Training
YHEC staff also offer training in systematic review skills and contribute to research into the development of systematic review methods.