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Peer-reviewed publication

Mitigating Bias in Health-Related Quality of Life (HRQoL) Estimation Due to Missing Data: A Simulation-Based Study Evaluating Imputation Methods

YHEC authors: Joe Moss, Neil Hansell, Erin Barker, Matthew Taylor

Publication date: August 2026

Publishers: MDPI

Journal: Health Economics & Policy

Abstract

Missing Health-Related Quality of Life (HRQoL) data in clinical studies risk propagating bias into health technology assessments (HTAs) and cost-utility analyses. Despite this, current National Institute for Health and Care...

Peer-reviewed publication

Cost-Effectiveness of Maternal RSVpreF Vaccination Compared with Newborn Nirsevimab RSV Prophylaxis or No RSV Prophylaxis in Switzerland

YHEC authors: Amy Dymond, Stuart Mealing, Charlotte Graham

Publication date: August 2026

Journal: Applied Health Economics and Health Policy

Abstract

BACKGROUND: RSVpreF is a vaccine that immunises against respiratory syncytial virus (RSV), a seasonal respiratory virus, that can lead to lower respiratory tract infections. In Switzerland, RSVpreF is indicated for...

Peer-reviewed publication

Eliciting Health State Utilities for Open Wounds in Dystrophic Epidermolysis Bullosa

YHEC authors: Damian Lewis, Adam B. Smith, Andria Joseph

Publication date: July 2026

Journal: Quality of Life Research

Abstract

PURPOSE: Qualitative accounts and studies employing disease-specific outcome measures have demonstrated that people with dystrophic epidermolysis bullosa (DEB) display impaired health-related quality of life (HRQoL) due to wound-related challenges. There...