Evaluating the Cost-Effectiveness of Integrated Smoking Cessation within Lung Cancer Screening, using a Health Economic Model

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Peer-reviewed publication

Eliciting Health State Utilities for Open Wounds in Dystrophic Epidermolysis Bullosa

YHEC authors: Damian Lewis, Adam B. Smith, Andria Joseph

Publication date: July 2026

Journal: Quality of Life Research

Abstract

PURPOSE: Qualitative accounts and studies employing disease-specific outcome measures have demonstrated that people with dystrophic epidermolysis bullosa (DEB) display impaired health-related quality of life (HRQoL) due to wound-related challenges. There...

Peer-reviewed publication

Cost-Effectiveness Analysis of Transcatheter Aortic Valve Implantation for Asymptomatic Severe Aortic Stenosis Across Nine European Countries

YHEC authors: Lucy Hillcoat, Heather Davies

Publication date: July 2026

Journal: European Heart Journal Open

Abstract

AIMS: Asymptomatic severe aortic stenosis (aSAS) is associated with morbidity, with mortality increasing once symptoms develop. Benefits of early aortic valve replacement (AVR) over clinical surveillance (CS) with delayed AVR...

Peer-reviewed publication

A Disease Progression Model Comparing the Long-Term Mobility and Respiratory Outcomes of Adults with Late-Onset Pompe Disease Receiving Cipaglucosidase Alfa Plus Miglustat versus Alglucosidase Alfa

YHEC authors: Amy Dymond, Will Green

Publication date: July 2026

Journal: Journal of Comparative Effectiveness Research

Abstract

AIM: Late-onset Pompe disease (LOPD) is a rare lysosomal disease primarily impacting muscle strength andrespiratory function. LOPD has a substantial burden despite the availability of alglucosidase alfa (alg). Patients often...