Published: March 2025
Last updated: March 2025
Congenital thrombotic thrombocytopenic purpura (cTTP) is an ultra rarehaematological disorder. This study aimed to estimate the clinical burden, healthcareresource use (HCRU) and associated costs of cTTP in England using primary...
BACKGROUND: The long-term use of strong opioids for chronic non-cancer pain puts people at risk of serious harm. OBJECTIVES: To test the effectiveness and cost-effectiveness of a multicomponent intervention targeting...
BACKGROUND: Modifiable risks—tobacco use, poor diet, alcohol consumption, physical inactivity and mental ill-health—drive substantial disease in UK. NICE evidence on preventive interventions targeting these risks and estimates of eligible populations...