Published: April 2024

Last updated: April 2024

How to Successfully Navigate Reimbursement in Rare Diseases: From Inception to Submission

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Peer-reviewed publication

Carbon Emission Impact of Semaglutide in People with Obesity in the UK Using a Disease Modelling Approach

YHEC authors: Matthew Taylor
Publication date: September 2026
Journal: PharmacoEconomics

Abstract

OBJECTIVE: We aimed to assess the carbon footprint and clinical outcomes of once-weekly semaglutide in people with overweight or obesity in the UK using a disease modelling approach. METHODS: A...

Peer-reviewed publication

Comparing Statistically Reliable and Patient-Perceived Improvement Following Hip Arthroplasty: Rasch-Based and Anchor-Based Approaches

YHEC authors: Adam Smith, Damian Lewis, Stuart Mealing, Andria Joseph
Publication date: September 2026
Journal: Journal of Patient Reported Outcomes

Abstract

BACKGROUND: Interpreting meaningful change in patient-reported outcome measures (PROMs) is essential for assessing hip replacement outcomes. The Oxford Hip Score (OHS) is widely used, yet statistically detectable change may not...

Peer-reviewed publication

Mitigating Bias in Health-Related Quality of Life (HRQoL) Estimation Due to Missing Data: A Simulation-Based Study Evaluating Imputation Methods

YHEC authors: Joe Moss, Neil Hansell, Erin Barker, Matthew Taylor
Publication date: August 2026
Publishers: MDPI
Journal: Health Economics & Policy

Abstract

Missing Health-Related Quality of Life (HRQoL) data in clinical studies risk propagating bias into health technology assessments (HTAs) and cost-utility analyses. Despite this, current National Institute for Health and Care...