Burden-of-illness review

Burden-of-illness reviews are conducted to comprehensively understand the impact of a particular disease. By reviewing the literature, these studies aim to quantify the disease burden (such as the incidence, prevalence, morbidity, mortality, frequency of clinical events), the humanistic burden (such as effects on health-related quality of life), and the economic burden (such as direct healthcare costs and indirect costs like lost productivity) associated with the condition, often within a specific geographic context.