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Our latest research, all in one place. Browse our collection of journal articles, reports and conference proceedings to see how we’re contributing to HEOR research. Remember to: 

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Report

Cost-Effectiveness of Hospital Design: Options to Improve Patient Safety and Wellbeing (Patient Safety Research Portfolio Project PS041)

YHEC authors: Karin Lowson, Matthew Bending, Sarah Whitehead, Dianne Wright, Paula Lowson, Steven Duffy
Publication date: November 2010

Abstract

No abstract available

Peer-reviewed publication

Estimating the Direct Costs of Bowel Cancer Services Provided by the National Health Service in England

YHEC authors: Matthew Bending, Karin Lowson
Publication date: November 2010
Journal: International Journal of Technology Assessment in Health Care

Abstract

OBJECTIVES: Bowel cancer is the second most common cancer in England and Wales, accounting for approximately 13,000 deaths per year. Economic evaluations and national guidance have been produced for individual treatments for bowel cancer. However, it has been suggested that Primary Care Trusts develop program budgeting or equivalent methodology demonstrating a whole system approach to investment and disinvestment. The objective of this study was to provide a baseline framework for considering a whole system approach to estimate the direct costs of bowel cancer services provided by the National Health Service (NHS) in England.

METHODS: A treatment pathway, developed in 2005, was used to construct a service pathway model to estimate the direct cost of bowel cancer services in England.

RESULTS: The service pathway model estimated the direct cost of bowel cancer services to the NHS to be in excess of £1 billion in 2005. Thirty-five percent of the cost is attributable to the screening and testing of patients with suspected bowel cancer, subsequently diagnosed as cancer-free.

CONCLUSIONS: This study is believed to be the most comprehensive attempt to identify the direct cost of managing bowel cancer services in England. The approach adopted could be useful to assist local decision makers in identifying those aspects of the pathway that are most uncertain in terms of their cost-effectiveness and as a basis to explore the implications of re-allocated resources. Research recommendations include the need for detailed costs on surgical procedures, high-risk patients and the utilization of the methods used in this study across other cancers.

Report

Evaluation of the Scale, Causes and Costs of Waste Medicines

YHEC authors: Paul Trueman, Karin Lowson, Alan Blighe, Agnes Meszaros, Dianne Wright, Julie Glanville
Publication date: November 2010
Publishers: YHEC

Abstract

No abstract available

Peer-reviewed publication

Identifying Economic Evaluations for Health Technology Assessment

YHEC authors: Julie Glanville
Publication date: October 2010
Journal: International Journal of Technology Assessment in Health Care

Abstract

OBJECTIVES AND METHODS: Health technology assessment (HTA) often requires the identification and review of economic evaluations and models. This study surveys the available specific and general resources to search to identify economic evaluations. It also provides information on efficient searching of those resources and comments on the current evidence-base.

RESULTS: Published checklists recommend searching for economic evaluations in specific information resources which collect economic evaluations such as NHS EED and HEED, followed by top-up searches of large biomedical bibliographic databases (such as MEDLINE and EMBASE). Other resources such as the HTA and DARE databases can yield reports of economic evaluations. Searches within NHS EED and HEED can be made more efficient by using database-specific search options. Searches within large biomedical databases such as MEDLINE and EMBASE require the use of economic search terms called search filters. Search filters are highly sensitive, retrieving most economic evaluations, but suffer from low precision returning many irrelevant records which need to be assessed.

CONCLUSIONS: It is relatively easy to identify rapidly a high proportion of economic evaluations but more research is required to improve the efficiency of this process. There are key high yield resources to search but more evidence is required on their overlap and unique contribution to searches. The value of other resources, particularly those providing access to gray literature, should be explored. Research into efficient retrieval requires clear definitions of economic evaluations to allow comparison across studies.

Peer-reviewed publication

The Initial Evaluation of the Scottish Telecare Development Programme

YHEC authors: Sophie Beale, Paul Truman, Diana Sanderson, Jen Kruger
Publication date: April 2010
Journal: Journal of Technology in Human Services

Abstract

In 2006 the Scottish Government provided just over £8 million to help 32 health and social care partnerships to develop telecare services. This paper presents a summary of the 2007-2008 evaluation of the Scottish Telecare Development. This evaluation focused on measuring overall program progress toward eight predefined Scottish Telecare Development objectives. Results indicate that the initial investment has resulted in significant savings to the health and social care sectors. Additionally, telecare provides opportunities to promote independence and improve the quality of life of service users and their informal carers. However, some caution needs to be taken in interpreting the findings as results are based on self-reported performance from partnerships, and many of the reported monetary "savings" are actually efficiency savings and are unlikely, in practice, to be cash-releasing.

Peer-reviewed publication

Cost-Effectiveness of the Endeavour Stent in de novo Native Coronary Artery Lesions Updated with Contemporary Data

YHEC authors: John Hutton
Publication date: February 2010
Journal: EuroIntervention

Abstract

AIMS: The Endeavor zotarolimus-eluting coronary stent has been shown to reduce the restenosis rate compared to bare metal stents and has impacted other clinical measures such as mortality, acute myocardial infarctions (AMI) and target vessel revascularisation (TVR).

METHODS AND RESULTS: Using pooled efficacy data from the Endeavor clinical trial programme, a model was developed to compare the cost effectiveness of the Endeavor drug eluting stent (DES) with the Driver bare meal stent (BMS) over a four year time period. Endeavor was more costly but had an improved clinical outcome compared to Driver BMS over four years with a 4% reduction in deaths, 33% reduction in AMI and a 45% reduction in TVR. Late stent thrombosis was the only event showing an increased incidence for Endeavor of 0.2% compared to 0% for Driver. The incremental cost effectiveness ratio was £3,757/quality adjusted life years (QALY).

CONCLUSIONS: Although much controversy has surrounded the appropriate way to assess the cost effectiveness of DES technology, a comprehensive analysis is presented and this suggests that by using extended clinical trial data out to four years, the Endeavor DES in particular, but DES technologies in general, are cost-effective approaches to percutaneous coronary intervention.

Peer-reviewed publication

The Economics of Pressure Relieving Surfaces: an Illustrative Case Study of the Impact of High-Specification Surfaces on Hospital Finances

YHEC authors: Paul Trueman, Sarah Whitehead
Publication date: February 2010
Journal: International Wound Care

Abstract

Pressure ulcers are associated with a significant economic burden that, in many cases, is recognised as being avoidable. The effectiveness of pressure relieving surfaces is well documented and acknowledged in clinical guidelines on the prevention and management of pressure ulcers. Whilst pressure relieving surfaces are more expensive than traditional hospital mattresses, judicious use, targeted to patients most at risk, can help to reduce the incidence and costs of pressure ulcers in hospital settings. This review paper includes a summary of pivotal clinical evidence on pressure relieving surfaces as well as a suggested approach for modelling their financial impact on hospital budgets. Simple financial modelling suggests that pressure relieving surfaces could lead to financial savings for a hospital when used appropriately.

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